SOX12 antibody

Catalog No. ABIN2460696

Product Details anti-SOX12 Antibody

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SOX12.

Application Details

Application Notes: SOX12 antibody can be used for detection of SOX12 by ELISA at 1:62500. SOX12 antibody can be used for detection of SOX12 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SOX12 antibody at -20 °C.

Target Details for SOX12

Target: SOX12 (SRY (Sex Determining Region Y)-Box 12 (SOX12))

Alternative Name: SOX12 (SOX12 Products)

Synonyms: SOX22 antibody, sox-k1 antibody, sox-k1-a antibody, sox33 antibody, xSox-33 antibody, xSox-K1 antibody, xSox33 antibody, 2010205A02Rik antibody, SRY-box 12 antibody, SRY box 12 antibody, SRY-box 12 S homeolog antibody, SRY (sex determining region Y)-box 12 antibody, SOX12 antibody, Sox12 antibody, sox12.S antibody

Background: Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types.

Molecular Weight: 34 kDa

Gene ID: 6666

NCBI Accession: NP_008874

UniProt: O15370