CAND1 antibody

Catalog No. ABIN2460995

Product Details anti-CAND1 Antibody

Target: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAND1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TIP120A.

Application Details

Application Notes: TIP120A antibody can be used for detection of TIP120A by ELISA at 1:62500. TIP120A antibody can be used for detection of TIP120A by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TIP120A antibody at -20 °C.

Target Details for CAND1

Target: CAND1 (Cullin-Associated and Neddylation-Dissociated 1 (CAND1))

Alternative Name: TIP120A (CAND1 Products)

Synonyms: TIP120 antibody, TIP120A antibody, ATCAND1 antibody, CULLIN-ASSOCIATED AND NEDDYLATION DISSOCIATED 1 antibody, ETA2 antibody, HEMIVENATA antibody, HVE antibody, T8K22.14 antibody, T8K22_14 antibody, cullin-associated and neddylation dissociated antibody, Tip120 antibody, Tip120A antibody, fb78a05 antibody, wu:fb78a05 antibody, zgc:55729 antibody, tip120 antibody, tip120a antibody, cand2 antibody, 2310038O07Rik antibody, 6330512O03Rik antibody, AI195005 antibody, AI846556 antibody, D10Ertd516e antibody, Tp120a antibody, mKIAA0829 antibody, cullin associated and neddylation dissociated 1 antibody, cullin-associated and neddylation dissociated antibody, cullin-associated and neddylation-dissociated 1 antibody, cullin-associated and neddylation-dissociated 1 L homeolog antibody, cullin-associated NEDD8-dissociated protein 1 antibody, cullin associated and neddylation disassociated 1 antibody, CAND1 antibody, Cand1 antibody, cand1 antibody, cand1.L antibody, LOC100159824 antibody, LOC100177977 antibody

Background: TIP120A functions as a negative regulator of SCF E3 ubiquitin ligases and may modulate other cullin ligases in a similar fashion.

Molecular Weight: 136 kDa

Gene ID: 55832

NCBI Accession: NP_060918

UniProt: Q86VP6

Pathways: Regulation of Actin Filament Polymerization