GABRE antibody

Catalog No. ABIN2461133

Product Details anti-GABRE Antibody

Target: GABRE (gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRE antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GABRE.

Application Details

Application Notes: GABRE antibody can be used for detection of GABRE by ELISA at 1:312500. GABRE antibody can be used for detection of GABRE by western blot at 2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GABRE antibody at -20 °C.

Target Details for GABRE

Target: GABRE (gamma-aminobutyric Acid (GABA) A Receptor, epsilon (GABRE))

Alternative Name: GABRE (GABRE Products)

Synonyms: GABRE antibody, gamma-aminobutyric acid type A receptor epsilon subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit epsilon antibody, GABRE antibody, Gabre antibody

Background: GABRE belongs to the ligand-gated ionic channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid (GABA) A receptor which is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes an epsilon subunit. It is mapped to chromosome Xq28 in a cluster comprised of genes encoding alpha 3, beta 4 and theta subunits of the same receptor. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 43 kDa, 58 kDa, 42 kDa, 46 kDa

Gene ID: 2564

NCBI Accession: NP_068819

UniProt: P78334

Pathways: Synaptic Membrane