DHX30 antibody

Catalog No. ABIN2461364

Product Details anti-DHX30 Antibody

Target: DHX30 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 30 (DHX30))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHX30 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DHX30.

Application Details

Application Notes: DHX30 antibody can be used for detection of DHX30 by ELISA at 1:62500. DHX30 antibody can be used for detection of DHX30 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DHX30 antibody at -20 °C.

Target Details for DHX30

Target: DHX30 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 30 (DHX30))

Alternative Name: DHX30 (DHX30 Products)

Synonyms: DHX30 antibody, dhx30 antibody, DDX30 antibody, RETCOR antibody, 2810477H02Rik antibody, C130058C04Rik antibody, Ddx30 antibody, HELG antibody, Ret-CoR antibody, DExH-box helicase 30 antibody, DEAH (Asp-Glu-Ala-His) box helicase 30 antibody, DEAH-box helicase 30 antibody, DEAH-box helicase 30 S homeolog antibody, DEAH (Asp-Glu-Ala-His) box polypeptide 30 antibody, DHX30 antibody, dhx30 antibody, dhx30.S antibody, Dhx30 antibody

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DHX30 is a member of this family.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a member of this family. The encoded protein has 97 % sequence identity with the mouse HELG protein. Alternative splicing of this gene generates 3 transcript variants.

Molecular Weight: 40 kDa

Gene ID: 22907

NCBI Accession: NP_619519

Pathways: Chromatin Binding