KCNAB2 antibody

Catalog No. ABIN2461572

Product Details anti-KCNAB2 Antibody

Target: KCNAB2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 2 (KCNAB2))

Reactivity: Rat, Human, Mouse, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNAB2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNAB2.

Application Details

Application Notes: KCNAB2 antibody can be used for detection of KCNAB2 by ELISA at 1:312500. KCNAB2 antibody can be used for detection of KCNAB2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KCNAB2 antibody at -20 °C.

Target Details for KCNAB2

Target: KCNAB2 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, beta Member 2 (KCNAB2))

Alternative Name: KCNAB2 (KCNAB2 Products)

Synonyms: kcnab2 antibody, KCNAB2 antibody, DKFZp459E056 antibody, akr6a5 antibody, kcna2b antibody, kvb-a antibody, kvb2 antibody, kvbeta2 antibody, kvbeta2.1 antibody, kvbeta2.2 antibody, AKR6A5 antibody, HKvbeta2 antibody, HKvbeta2.1 antibody, HKvbeta2.2 antibody, KCNA2B antibody, KV-BETA-2 antibody, Kvbeta2.1 antibody, F5 antibody, I2rf5 antibody, Kcnb3 antibody, kv-beta-2 antibody, potassium channel, voltage gated subfamily A regulatory beta subunit 1 antibody, potassium voltage-gated channel subfamily A regulatory beta subunit 2 antibody, potassium voltage-gated channel, shaker-related subfamily, beta member 2 a antibody, potassium channel, voltage gated subfamily A regulatory beta subunit 2 L homeolog antibody, voltage-gated potassium channel subunit beta-2 antibody, potassium voltage-gated channel, shaker-related subfamily, beta member 2 antibody, kcnab1 antibody, KCNAB2 antibody, kcnab2a antibody, kcnab2.L antibody, LOC397248 antibody, Kcnab2 antibody

Background: This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms.

Molecular Weight: 40 kDa, 39 kDa

Gene ID: 8514

NCBI Accession: NP_003627

UniProt: Q13303