BACH1 antibody

Catalog No. ABIN2461624

Product Details anti-BACH1 Antibody

Target: BACH1 (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BACH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human BACH1.

Application Details

Application Notes: BACH1 antibody can be used for detection of BACH1 by ELISA at 1:1562500. BACH1 antibody can be used for detection of BACH1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store BACH1 antibody at -20 °C.

Target Details for BACH1

Target: BACH1 (BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1))

Alternative Name: BACH1 (BACH1 Products)

Synonyms: zgc:112205 antibody, BACH1 antibody, 6230421P05Rik antibody, AI323795 antibody, BACH-1 antibody, BTB domain and CNC homolog 1 antibody, BTB and CNC homology 1, basic leucine zipper transcription factor 1 b antibody, BTB and CNC homology 1, basic leucine zipper transcription factor 1 antibody, BACH1 antibody, bach1b antibody, bach1 antibody, Bach1 antibody

Background: BACH1 is a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. Some exons of this gene overlap with some exons from the C21orf41 gene, which is transcribed in an opposite orientation to this gene but does not seem to encode a protein.

Molecular Weight: 82 kDa, 82 kDa

Gene ID: 571

NCBI Accession: NP_001177

UniProt: O14867