SART3 antibody

Catalog No. ABIN2461855

Product Details anti-SART3 Antibody

Target: SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SART3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SART3.

Application Details

Application Notes: SART3 antibody can be used for detection of SART3 by ELISA at 1:62500. SART3 antibody can be used for detection of SART3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SART3 antibody at -20 °C.

Target Details for SART3

Target: SART3 (Squamous Cell Carcinoma Antigen Recognized By T Cells 3 (SART3))

Alternative Name: SART3 (SART3 Products)

Synonyms: SART3 antibody, DKFZp469J2418 antibody, si:ch211-191d15.4 antibody, wu:fc51h03 antibody, DSAP1 antibody, P100 antibody, RP11-13G14 antibody, TIP110 antibody, p110 antibody, p110(nrb) antibody, AU045857 antibody, mKIAA0156 antibody, squamous cell carcinoma antigen recognized by T-cells 3 antibody, squamous cell carcinoma antigen recognized by T-cells 3 L homeolog antibody, squamous cell carcinoma antigen recognized by T cells 3 antibody, SART3 antibody, sart3 antibody, sart3.L antibody, Sart3 antibody

Background: SART3 is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. SART3 is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This protein is thought to be involved in the regulation of mRNA splicing.

Molecular Weight: 40 kDa, 110 kDa

Gene ID: 9733

Pathways: Ribonucleoprotein Complex Subunit Organization