GATAD2B antibody

Catalog No. ABIN2461904

Product Details anti-GATAD2B Antibody

Target: GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GATAD2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GATAD2B.

Application Details

Application Notes: GATAD2B antibody can be used for detection of GATAD2B by ELISA at 1:312500. GATAD2B antibody can be used for detection of GATAD2B by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GATAD2B antibody at -20 °C.

Target Details for GATAD2B

Target: GATAD2B (GATA Zinc Finger Domain Containing 2B (GATAD2B))

Alternative Name: GATAD2B (GATAD2B Products)

Synonyms: GATAD2B antibody, MRD18 antibody, P66beta antibody, RP11-216N14.6 antibody, p68 antibody, AL118180 antibody, C430014D17Rik antibody, mKIAA1150 antibody, RGD1308533 antibody, GATA zinc finger domain containing 2B antibody, GATAD2B antibody, gatad2b antibody, Gatad2b antibody

Background: Hp66beta (GATAD2B), previously identified as a component of the human MeCP1 complex, is a second member of a p66 gene family (hp66alpha and hp66beta). Both proteins interact with MBD2 and MBD3 functionally and biochemically. Both factors function in synergy, since knocking-down p66alpha affects the repressive function of p66beta and vice versa. Furthermore, confocal microscopy shows a nuclear colocalization of hp66alpha with hp66beta and MBD2 in a speckled pattern. These two highly related mammalian p66 proteins display overlapping functions and are involved in methylation dependent transcriptional repression.

Molecular Weight: 65 kDa

Gene ID: 57459

NCBI Accession: NP_065750

UniProt: Q8WXI9