HMBOX1 antibody

Catalog No. ABIN2461931

Product Details anti-HMBOX1 Antibody

Target: HMBOX1 (Homeobox Containing 1 (HMBOX1))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMBOX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HMBOX1.

Application Details

Application Notes: HMBOX1 antibody can be used for detection of HMBOX1 by ELISA at 1:312500. HMBOX1 antibody can be used for detection of HMBOX1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store HMBOX1 antibody at -20 °C.

Target Details for HMBOX1

Target: HMBOX1 (Homeobox Containing 1 (HMBOX1))

Alternative Name: HMBOX1 (HMBOX1 Products)

Synonyms: pbhnf antibody, hnf1la antibody, MGC81685 antibody, hmbox1 antibody, HNF1LA antibody, HOT1 antibody, PBHNF antibody, AI451877 antibody, AI604847 antibody, F830020C16Rik antibody, RGD1306787 antibody, zgc:114064 antibody, homeobox containing 1 S homeolog antibody, homeobox containing 1 antibody, homeobox containing 1 L homeolog antibody, homeobox containing 1a antibody, hmbox1.S antibody, HMBOX1 antibody, hmbox1.L antibody, Hmbox1 antibody, hmbox1a antibody

Background: HMBOX1 is located at the boundary of 8p12.3 and 8p21.1. HMBOX1 proteins are highly conserved in human, mouse, rat, chicken and Xenopus laevis. Functional HMBOX1::EGFP (enhanced green fluorescent protein) fusion protein revealed that HMBOX1 accumulated more in cytoplasm than in nucleus. HMBOX1 is a transcription repressor. Human HMBOX1 is widely expressed in 18 tissues, and it is highly expressed in pancreas. Hmbox1 is widely expressed in mouse pancreas and the expression of this gene can also be detected in pallium, hippocampus and hypothalamus.

Molecular Weight: 47 kDa

Gene ID: 79618

NCBI Accession: NP_078843

UniProt: Q6NT76