GNB1L antibody

Catalog No. ABIN2462388

Product Details anti-GNB1L Antibody

Target: GNB1L (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1-Like (GNB1L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNB1L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GNB1L.

Application Details

Application Notes: GNB1L antibody can be used for detection of GNB1L by ELISA at 1:12500. GNB1L antibody can be used for detection of GNB1L by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store GNB1L antibody at -20 °C.

Target Details for GNB1L

Target: GNB1L (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1-Like (GNB1L))

Alternative Name: GNB1L (GNB1L Products)

Synonyms: DGCRK3 antibody, GY2 antibody, WDR14 antibody, WDVCF antibody, ESTM55 antibody, Gm16314 antibody, Me49f07 antibody, OTTMUSG00000033458 antibody, Wdr14 antibody, Wdvcf antibody, GNB1L antibody, zgc:110763 antibody, G protein subunit beta 1 like antibody, guanine nucleotide binding protein (G protein), beta polypeptide 1-like antibody, GNB1L antibody, Gnb1l antibody, gnb1l antibody

Background: GNB1L is a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. Therefore, this gene may contribute to the etiology of those disorders.This gene encodes a G-protein beta-subunit-like polypeptide which is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 6 WD repeats and is highly expressed in the heart. The gene maps to the region on chromosome 22q11, which is deleted in DiGeorge syndrome, trisomic in derivative 22 syndrome and tetrasomic in cat-eye syndrome. Therefore, this gene may contribute to the etiology of those disorders.

Molecular Weight: 36 kDa

Gene ID: 54584

NCBI Accession: NP_443730

UniProt: Q9BYB4