UROD antibody

Catalog No. ABIN2462463

Product Details anti-UROD Antibody

Target: UROD (Uroporphyrinogen Decarboxylase (UROD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UROD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human UROD.

Application Details

Application Notes: UROD antibody can be used for detection of UROD by ELISA at 1:62500. UROD antibody can be used for detection of UROD by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store UROD antibody at -20 °C.

Target Details for UROD

Target: UROD (Uroporphyrinogen Decarboxylase (UROD))

Alternative Name: UROD (UROD Products)

Synonyms: UROD antibody, pct antibody, wu:fc43e09 antibody, PCT antibody, UPD antibody, AI323803 antibody, Uro-d antibody, porphyrinogen carboxy-lyase antibody, uroporphyrinogen decarboxylase antibody, Uroporphyrinogen decarboxylase UroD antibody, Uroporphyrinogen decarboxylase antibody, UROD antibody, urod antibody, hemE antibody, uroD antibody, Cpin_6502 antibody, Rmar_1187 antibody, LOC5568261 antibody, Mrub_1403 antibody, Arnit_2230 antibody, Ndas_2830 antibody, Mesil_2989 antibody, Trad_0222 antibody, Weevi_0432 antibody, Hipma_1229 antibody, Fluta_0529 antibody, Marky_1143 antibody, Halhy_5610 antibody, Mesop_0899 antibody, Ccan_20670 antibody, Urod antibody

Background: UROD is the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.This gene encodes the fifth enzyme of the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.

Molecular Weight: 40 kDa

Gene ID: 7389

NCBI Accession: NP_000365

UniProt: P06132