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SLC19A1 antibody

SLC19A1 Reactivity: Human WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2462787
  • Target See all SLC19A1 Antibodies
    SLC19A1 (Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1))
    Reactivity
    • 18
    • 10
    • 2
    Human
    Host
    • 24
    • 1
    • 1
    Rabbit
    Clonality
    • 26
    Polyclonal
    Conjugate
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC19A1 antibody is un-conjugated
    Application
    • 23
    • 13
    • 13
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Purification
    Antibody is purified by protein A chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SLC19A1.
    Top Product
    Discover our top product SLC19A1 Primary Antibody
  • Application Notes
    SLC19A1 antibody can be used for detection of SLC19A1 by ELISA at 1:1562500. SLC19A1 antibody can be used for detection of SLC19A1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store SLC19A1 antibody at -20 °C.
  • Target
    SLC19A1 (Solute Carrier Family 19 (Folate Transporter), Member 1 (SLC19A1))
    Alternative Name
    SLC19A1 (SLC19A1 Products)
    Synonyms
    A1 antibody, MHCBFB antibody, PO-GA antibody, RECC1 antibody, RFC antibody, RFC140 antibody, CHMD antibody, FOLT antibody, IFC1 antibody, REFC antibody, RFC1 antibody, LOC100226745 antibody, AI323572 antibody, RFC-1 antibody, MTX1 antibody, XRFC antibody, chmd antibody, folt antibody, ifc1 antibody, refc antibody, rfc1 antibody, slc19a1 antibody, replication factor C subunit 1 antibody, solute carrier family 19 member 1 antibody, folate transporter 1 antibody, solute carrier family 19 (folate transporter), member 1 antibody, solute carrier family 19 (folate transporter), member 1 L homeolog antibody, RFC1 antibody, SLC19A1 antibody, LOC100226745 antibody, Slc19a1 antibody, slc19a1.L antibody
    Background
    Transport of folate compounds into mammalian cells can occur via receptor-mediated or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. SLC19A1 plays a role in maintaining intracellular concentrations of folate.Transport of folate compounds into mammalian cells can occur via receptor-mediated (see MIM 136430) or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.
    Molecular Weight
    65 kDa
    Gene ID
    6573
    NCBI Accession
    NP_919231
    UniProt
    P41440
    Pathways
    Dicarboxylic Acid Transport
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