MTUS1 antibody

Catalog No. ABIN2462816

Product Details anti-MTUS1 Antibody

Target: MTUS1 (Microtubule Associated Tumor Suppressor 1 (MTUS1))

Reactivity: Human, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTUS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MTUS1.

Application Details

Application Notes: MTUS1 antibody can be used for detection of MTUS1 by ELISA at 1:1562500. MTUS1 antibody can be used for detection of MTUS1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MTUS1 antibody at -20 °C.

Target Details for MTUS1

Target: MTUS1 (Microtubule Associated Tumor Suppressor 1 (MTUS1))

Alternative Name: MTUS1 (MTUS1 Products)

Synonyms: ATBP antibody, ATIP antibody, ICIS antibody, MP44 antibody, MTSG1 antibody, AI481402 antibody, ATBP135 antibody, Atip1 antibody, B430010I23Rik antibody, B430305I03Rik antibody, C85752 antibody, Cctsg1-440 antibody, MD44 antibody, mKIAA1288 antibody, ATIP4 antibody, Atip3b antibody, Mtsg1 antibody, fbx27 antibody, fa17d11 antibody, wu:fa17d11 antibody, wu:fi18f08 antibody, zgc:154168 antibody, microtubule associated scaffold protein 1 antibody, mitochondrial tumor suppressor 1 antibody, microtubule associated scaffold protein 1 L homeolog antibody, microtubule associated tumor suppressor 1 antibody, microtubule associated tumor suppressor 1a antibody, MTUS1 antibody, Mtus1 antibody, mtus1.L antibody, mtus1a antibody

Background: MTUS1 contains a C-terminal domain and is able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. One of the isoforms has been shown to be a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other isoforms may be nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.

Molecular Weight: 48 kDa, 141 kDa, 136 kDa, 59 kDa

Gene ID: 57509

NCBI Accession: NP_065800