AOC2 antibody

Catalog No. ABIN2462830

Product Details anti-AOC2 Antibody

Target: AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AOC2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AOC2.

Application Details

Application Notes: AOC2 antibody can be used for detection of AOC2 by ELISA at 1:312500. AOC2 antibody can be used for detection of AOC2 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store AOC2 antibody at -20 °C.

Target Details for AOC2

Target: AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))

Alternative Name: AOC2 (AOC2 Products)

Synonyms: DAO2 antibody, RAO antibody, AOC2 antibody, AOC3 antibody, aoc3 antibody, wu:fa94a08 antibody, wu:fe14c05 antibody, zgc:113006 antibody, amine oxidase, copper containing 2 antibody, amine oxidase, copper containing 2 (retina-specific) antibody, membrane primary amine oxidase-like antibody, retina-specific copper amine oxidase antibody, AOC2 antibody, Aoc2 antibody, LOC100353051 antibody, aoc2 antibody

Background: Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine.Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.

Molecular Weight: 84 kDa, 81 kDa

Gene ID: 314

NCBI Accession: NP_033720

UniProt: O75106