ALDH4A1 antibody

Catalog No. ABIN2462884

Product Details anti-ALDH4A1 Antibody

Target: ALDH4A1 (Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1))

Reactivity: Human, Mouse, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH4A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ALDH4A1.

Application Details

Application Notes: ALDH4A1 antibody can be used for detection of ALDH4A1 by ELISA at 1:312500. ALDH4A1 antibody can be used for detection of ALDH4A1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ALDH4A1 antibody at -20 °C.

Target Details for ALDH4A1

Target: ALDH4A1 (Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1))

Alternative Name: ALDH4A1 (ALDH4A1 Products)

Synonyms: aldh4 antibody, p5cd antibody, p5cdh antibody, ALDH4 antibody, P5CD antibody, P5CDh antibody, A930035F14Rik antibody, Ahd-1 antibody, Ahd1 antibody, Aldh4 antibody, Aldh5a1 antibody, E330022C09 antibody, P5cd antibody, P5cdh antibody, P5cdhl antibody, P5cdhs antibody, Ssdh1 antibody, zgc:63592 antibody, aldehyde dehydrogenase 4 family member A1 antibody, aldehyde dehydrogenase 4 family, member A1 antibody, aldehyde dehydrogenase 4 family member A1 L homeolog antibody, aldh4a1 antibody, ALDH4A1 antibody, Aldh4a1 antibody, aldh4a1.L antibody

Background: ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline.This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Two transcript variants encoding the same protein have been identified for this gene.

Molecular Weight: 62 kDa, 62 kDa

Gene ID: 8659

NCBI Accession: NP_003739

UniProt: P30038

Pathways: Monocarboxylic Acid Catabolic Process