C21orf33 antibody

Catalog No. ABIN2462904

Product Details anti-C21orf33 Antibody

Target: C21orf33 (Chromosome 21 Open Reading Frame 33 (C21orf33))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C21orf33 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human C21orf33.

Application Details

Application Notes: C21orf33 antibody can be used for detection of C21orf33 by ELISA at 1:1562500. C21orf33 antibody can be used for detection of C21orf33 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store C21orf33 antibody at -20 °C.

Target Details for C21orf33

Target: C21orf33 (Chromosome 21 Open Reading Frame 33 (C21orf33))

Alternative Name: C21orf33 (C21orf33 Products)

Synonyms: C21orf33 antibody, es1 antibody, knph antibody, knpi antibody, ES1 antibody, GT335 antibody, HES1 antibody, KNPH antibody, KNPI antibody, chromosome 21 open reading frame, human C21orf33 antibody, chromosome 1 open reading frame, human C21orf33 antibody, chromosome 3 open reading frame, human C21orf33 antibody, chromosome 21 open reading frame 33 antibody, chromosome 21 open reading frame 33 L homeolog antibody, DNA segment, Chr 10, Johns Hopkins University 81 expressed antibody, homolog of zebrafish ES1 antibody, C21H21orf33 antibody, C1H21ORF33 antibody, C3H21orf33 antibody, c21orf33 antibody, C1H21orf33 antibody, c21orf33.L antibody, C21orf33 antibody, D10Jhu81e antibody, RGD1303003 antibody

Background: C21orf33 inhibits both estrogen- and heregulin-beta1-stimulated growth of breast cancer cells, and further suggests that growth inhibition induced in these cells by all-trans retinoic acid occurs via HES-1-mediated downregulation of E2F-1 expression. C21orf33 may also be a candidate protein involved in the pathogenesis of the brain deficit in DS.

Molecular Weight: 21 kDa, 28 kDa

Gene ID: 8209

NCBI Accession: NP_937798