TMPRSS11D antibody

Catalog No. ABIN2462980

Product Details anti-TMPRSS11D Antibody

Target: TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS11D antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TMPRSS11D.

Application Details

Application Notes: TMPRSS11D antibody can be used for detection of TMPRSS11D by ELISA at 1:62500. TMPRSS11D antibody can be used for detection of TMPRSS11D by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TMPRSS11D antibody at -20 °C.

Target Details for TMPRSS11D

Target: TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))

Alternative Name: TMPRSS11D (TMPRSS11D Products)

Synonyms: HAT antibody, AST antibody, AsP antibody, BC020151 antibody, Asp antibody, Tmprss11d antibody, transmembrane protease, serine 11D antibody, transmembrane protease, serine 11d antibody, transmembrane protease serine 11D antibody, TMPRSS11D antibody, Tmprss11d antibody, LOC100720850 antibody

Background: TMPRSS11D is a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38 % identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38 % identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.

Molecular Weight: 46 kDa

Gene ID: 9407

NCBI Accession: NP_004253

UniProt: O60235

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process