DDOST antibody

Catalog No. ABIN2462987

Product Details anti-DDOST Antibody

Target: DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDOST antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DDOST.

Application Details

Application Notes: DDOST antibody can be used for detection of DDOST by ELISA at 1:62500. DDOST antibody can be used for detection of DDOST by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DDOST antibody at -20 °C.

Target Details for DDOST

Target: DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))

Alternative Name: DDOST (DDOST Products)

Synonyms: AGER1 antibody, CDG1R antibody, OKSWcl45 antibody, OST antibody, OST48 antibody, WBP1 antibody, DDOST antibody, wu:fa11d01 antibody, zgc:66068 antibody, zgc:77478 antibody, Ddost antibody, CG9022 antibody, DmOST50 antibody, Dmel\\CG9022 antibody, DrOST antibody, OST48/WBP1 antibody, Ots48 antibody, anon-EST:Liang-1.11 antibody, clone 1.11 antibody, ost48 antibody, dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit antibody, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) S homeolog antibody, dolichyl-diphosphooligosaccharide-protein glycosyltransferase antibody, dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) antibody, dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit antibody, dolichyl-di-phosphooligosaccharide-protein glycotransferase antibody, Oligosaccharyltransferase 48kD subunit antibody, DDOST antibody, ddost.S antibody, GTR26 antibody, ddost antibody, Ddost antibody, LOC5580056 antibody, PTRG_01946 antibody, Ost48 antibody

Background: DDOST is a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.

Molecular Weight: 46 kDa

Gene ID: 1650

NCBI Accession: NP_005207

UniProt: Q5VWA5

Pathways: Cell RedoxHomeostasis