Corin antibody

Catalog No. ABIN2463005

Product Details anti-Corin Antibody

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Corin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CORIN.

Application Details

Application Notes: CORIN antibody can be used for detection of CORIN by ELISA at 1:312500. CORIN antibody can be used for detection of CORIN by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CORIN antibody at -20 °C.

Target Details for Corin

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Alternative Name: CORIN (CORIN Products)

Synonyms: CORIN antibody, CG2105 antibody, Dmel\\CG2105 antibody, SP75 antibody, LOC559109 antibody, AV273130 antibody, Lrp4 antibody, ATC2 antibody, CRN antibody, PEE5 antibody, TMPRSS10 antibody, corin, serine peptidase antibody, CG2105 gene product from transcript CG2105-RC antibody, novel protein similar to H.sapiens CORIN, corin, serine peptidase (CORIN) antibody, corin antibody, CORIN antibody, Corin antibody, LOC559109 antibody

Background: CORIN is a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. CORIN converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.

Molecular Weight: 74 kDa, 116 kDa

Gene ID: 10699

UniProt: Q9Y5Q5

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones