SMC3 antibody

Catalog No. ABIN2463080

Product Details anti-SMC3 Antibody

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMC3.

Application Details

Application Notes: SMC3 antibody can be used for detection of SMC3 by ELISA at 1:62500. SMC3 antibody can be used for detection of SMC3 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SMC3 antibody at -20 °C.

Target Details for SMC3

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Alternative Name: SMC3 (SMC3 Products)

Synonyms: cspg6 antibody, xsmc3 antibody, BAM antibody, BMH antibody, CDLS3 antibody, CSPG6 antibody, HCAP antibody, SMC3L1 antibody, Bamacan antibody, Cspg6 antibody, Mmip1 antibody, SMC-3 antibody, SmcD antibody, im:7142991 antibody, wu:fb22e01 antibody, wu:fc30d07 antibody, bamacan antibody, structural maintenance of chromosomes 3 antibody, structural maintenance of chromosomes 3 S homeolog antibody, smc3 antibody, SMC3 antibody, Smc3 antibody, smc3.S antibody

Background: SMC3 belongs to the SMC3 subfamily of SMC proteins. SMC3 occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation.

Molecular Weight: 74 kDa

Gene ID: 9126

UniProt: Q9UQE7

Pathways: Stem Cell Maintenance