FNTA antibody

Catalog No. ABIN2463191

Product Details anti-FNTA Antibody

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNTA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FNTA.

Application Details

Application Notes: FNTA antibody can be used for detection of FNTA by ELISA at 1:62500. FNTA antibody can be used for detection of FNTA by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FNTA antibody at -20 °C.

Target Details for FNTA

Target: FNTA (Farnesyltransferase, CAAX Box, alpha (FNTA))

Alternative Name: FNTA (FNTA Products)

Synonyms: ATFTA antibody, FARNESYLTRANSFERASE A antibody, FARNESYLTRANSFERASE SUBUNIT A antibody, PFT/PGGT-IALPHA antibody, PLP antibody, PLURIPETALA antibody, farnesyltransferase A antibody, FPTA antibody, PGGT1A antibody, PTAR2 antibody, PFAS antibody, FTA antibody, farnesyltransferase A antibody, farnesyltransferase, CAAX box, alpha antibody, FTA antibody, FNTA antibody, Fnta antibody

Background: Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. FNTA is the alpha subunit of these transferases.Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box. CAAX geranylgeranyltransferase and CAAX farnesyltransferase are heterodimers that share the same alpha subunit but have different beta subunits. This gene encodes the alpha subunit of these transferases. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 36 kDa

Gene ID: 2339

NCBI Accession: NP_001018197

UniProt: A6NJW0

Pathways: Response to Water Deprivation, Regulation of G-Protein Coupled Receptor Protein Signaling