LIAS antibody

Catalog No. ABIN2463206

Product Details anti-LIAS Antibody

Target: LIAS (Lipoic Acid Synthetase (LIAS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LIAS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LIAS.

Application Details

Application Notes: LIAS antibody can be used for detection of LIAS by ELISA at 1:62500. LIAS antibody can be used for detection of LIAS by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store LIAS antibody at -20 °C.

Target Details for LIAS

Target: LIAS (Lipoic Acid Synthetase (LIAS))

Alternative Name: LIAS (LIAS Products)

Synonyms: LAS antibody, LIP1 antibody, LS antibody, PDHLD antibody, 2900022L22Rik antibody, 4933425M12Rik antibody, 7a5ex antibody, C77512 antibody, mLip1 antibody, zgc:66080 antibody, Lip-syn antibody, lipoyl synthase, mitochondrial antibody, lipoic acid synthetase antibody, lipoyl synthase antibody, lipoic acid synthetase S homeolog antibody, Lipoyl synthase, mitochondrial antibody, LOC5571879 antibody, THAPSDRAFT_31845 antibody, THAPSDRAFT_31673 antibody, UREG_00501 antibody, LOAG_04019 antibody, TERG_02451 antibody, Tsp_01534 antibody, LIAS antibody, Lias antibody, lias antibody, lias.S antibody, umc2251 antibody

Background: LIAS belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha- (+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis.The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha- (+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

Molecular Weight: 39 kDa

Gene ID: 11019

NCBI Accession: NP_006850

UniProt: O43766

Pathways: Tube Formation