NMNAT1 antibody

Catalog No. ABIN2463228

Product Details anti-NMNAT1 Antibody

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NMNAT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NMNAT1.

Application Details

Application Notes: NMNAT1 antibody can be used for detection of NMNAT1 by ELISA at 1:12500. NMNAT1 antibody can be used for detection of NMNAT1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NMNAT1 antibody at -20 °C.

Target Details for NMNAT1

Target: NMNAT1 (Nicotinamide Nucleotide Adenylyltransferase 1 (NMNAT1))

Alternative Name: NMNAT1 (NMNAT1 Products)

Synonyms: id:ibd5068 antibody, im:7144541 antibody, zgc:110243 antibody, LCA9 antibody, NMNAT antibody, PNAT1 antibody, 2610529L11Rik antibody, 5730441G13Rik antibody, D4Cole1e antibody, nmnat antibody, nicotinamide mononucleotide adenylyltransferase 1 antibody, nicotinamide nucleotide adenylyltransferase 1 antibody, CpipJ_CPIJ015320 antibody, PTRG_06486 antibody, nmnat1 antibody, NMNAT1 antibody, Nmnat1 antibody

Background: The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca (2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD.The coenzyme NAD and its derivatives are involved in hundreds of metabolic redox reactions and are utilized in protein ADP-ribosylation, histone deacetylation, and in some Ca (2+) signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD biosynthesis, catalyzing the condensation of nicotinamide mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003 [PubMed 12574164]).

Molecular Weight: 32 kDa

Gene ID: 64802

NCBI Accession: NP_073624

UniProt: Q9HAN9