LTC4S antibody

Catalog No. ABIN2463252

Product Details anti-LTC4S Antibody

Target: LTC4S (Leukotriene C4 Synthase (LTC4S))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LTC4S antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human LTC4S.

Application Details

Application Notes: LTC4S antibody can be used for detection of LTC4S by ELISA at 1:1562500. LTC4S antibody can be used for detection of LTC4S by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store LTC4S antibody at -20 °C.

Target Details for LTC4S

Target: LTC4S (Leukotriene C4 Synthase (LTC4S))

Alternative Name: LTC4S (LTC4S Products)

Synonyms: LTC4S antibody, ltc4s antibody, si:dkey-33h4.2 antibody, leukotriene C4 synthase antibody, leukotriene C4 synthase-like antibody, leukotriene C4 synthase, gene 1 antibody, Ltc4s antibody, LTC4S antibody, LTC4SL antibody, ltc4s.1 antibody, ltc4s antibody

Background: The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. LTC4S is an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma.The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 16 kDa

Gene ID: 4056

NCBI Accession: NP_665874

UniProt: Q16873

Pathways: Cellular Response to Molecule of Bacterial Origin