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SEMA6D antibody

SEMA6D Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2463280
  • Target See all SEMA6D Antibodies
    SEMA6D (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D))
    Reactivity
    • 36
    • 34
    • 20
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Human, Mouse, Rat
    Host
    • 49
    • 2
    Rabbit
    Clonality
    • 51
    Polyclonal
    Conjugate
    • 18
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SEMA6D antibody is un-conjugated
    Application
    • 26
    • 20
    • 13
    • 13
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by peptide affinity chromatography method.
    Immunogen
    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SEMA6D.
    Top Product
    Discover our top product SEMA6D Primary Antibody
  • Application Notes
    SEMA6D antibody can be used for detection of SEMA6D by ELISA at 1:312500. SEMA6D antibody can be used for detection of SEMA6D by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
    Concentration
    1 mg/mL
    Buffer
    Antibody is lyophilized in PBS buffer with 2 % sucrose.
    Handling Advice
    As with any antibody avoid repeat freeze-thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    For short periods of storage (days) store at 4 °C. For longer periods of storage, store SEMA6D antibody at -20 °C.
  • Target
    SEMA6D (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D))
    Alternative Name
    SEMA6D (SEMA6D Products)
    Synonyms
    1110067B02Rik antibody, AA409156 antibody, D330011G23 antibody, Sema6D-1 antibody, Sema6D-2 antibody, Sema6D-4 antibody, Sema6D-5 antibody, Sema6D-6 antibody, mKIAA1479 antibody, wu:fi06a12 antibody, wu:fi76a10 antibody, zgc:56170 antibody, semaphorin 6D antibody, sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D antibody, semaphorin 6D L homeolog antibody, SEMA6D antibody, Sema6d antibody, sema6d antibody, sema6d.L antibody
    Background
    Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphoring domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.
    Molecular Weight
    52 kDa
    Gene ID
    80031
    NCBI Accession
    NP_079242
    UniProt
    Q8NFY4
    Pathways
    Smooth Muscle Cell Migration
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