PHF6 antibody

Catalog No. ABIN2463418

Product Details anti-PHF6 Antibody

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PHF6.

Application Details

Application Notes: PHF6 antibody can be used for detection of PHF6 by ELISA at 1:312500. PHF6 antibody can be used for detection of PHF6 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PHF6 antibody at -20 °C.

Target Details for PHF6

Target: PHF6 (PHD Finger Protein 6 (PHF6))

Alternative Name: PHF6 (PHF6 Products)

Synonyms: zgc:55403 antibody, wu:fa22g03 antibody, BFLS antibody, BORJ antibody, CENP-31 antibody, 2700007B13Rik antibody, 4931428F02Rik antibody, mKIAA1823 antibody, PHD finger protein 6 antibody, PHD finger protein 6 L homeolog antibody, phf6 antibody, phf6.L antibody, PHF6 antibody, Phf6 antibody

Background: PHF6 is a member of the plant homeodomain (PHD)-like finger (PHF) family. PHF6 is a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of its gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS).This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight: 35 kDa, 41 kDa, 41 kDa

Gene ID: 84295

NCBI Accession: NP_115711

UniProt: Q8IWS0