TRIP6 antibody

Catalog No. ABIN2463436

Product Details anti-TRIP6 Antibody

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIP6.

Application Details

Application Notes: TRIP6 antibody can be used for detection of TRIP6 by ELISA at 1:1562500. TRIP6 antibody can be used for detection of TRIP6 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TRIP6 antibody at -20 °C.

Target Details for TRIP6

Target: TRIP6 (Thyroid Hormone Receptor Interactor 6 (TRIP6))

Alternative Name: TRIP6 (TRIP6 Products)

Synonyms: TRIP6 antibody, OIP-1 antibody, OIP1 antibody, TRIP-6 antibody, TRIP6i2 antibody, ZRP-1 antibody, thyroid hormone receptor interactor 6 antibody, TRIP6 antibody, Trip6 antibody

Background: TRIP6 is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of TRIP6 to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration.This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 50 kDa

Gene ID: 7205

NCBI Accession: NP_003293

UniProt: Q15654

Pathways: Cell-Cell Junction Organization