SPAG11B antibody

Catalog No. ABIN2463598

Product Details anti-SPAG11B Antibody

Target: SPAG11B (Sperm Associated Antigen 11B (SPAG11B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPAG11B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SPAG11B.

Application Details

Application Notes: SPAG11B antibody can be used for detection of SPAG11B by ELISA at 1:312500. SPAG11B antibody can be used for detection of SPAG11B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SPAG11B antibody at -20 °C.

Target Details for SPAG11B

Target: SPAG11B (Sperm Associated Antigen 11B (SPAG11B))

Alternative Name: SPAG11B (SPAG11B Products)

Synonyms: EDDM2B antibody, EP2 antibody, EP2C antibody, EP2D antibody, HE2 antibody, HE2C antibody, SPAG11 antibody, Bin1b antibody, Spag11 antibody, Ep2c/h antibody, EG546038 antibody, Spag11c/h antibody, SPAG11B antibody, 9230111C08Rik antibody, EP2Q antibody, EP2e antibody, sperm associated antigen 11B antibody, sperm associated antigen 11A antibody, SPAG11B antibody, Spag11a antibody, Spag11b antibody

Background: SPAG11B is one of several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides.This gene encodes several androgen-dependent, epididymis-specific secretory proteins. The specific functions of these proteins have not been determined, but they are thought to be involved in sperm maturation. Some of the isoforms contain regions of similarity to beta-defensins, a family of antimicrobial peptides. The gene is located on chromosome 8p23 near the defensin gene cluster. Alternative splicing of this gene results in seven transcript variants encoding different isoforms. Two different N-terminal and five different C-terminal protein sequences are encoded by the splice variants. Two additional variants have been described, but their full length sequences have not been determined.

Molecular Weight: 15 kDa

Gene ID: 10407

NCBI Accession: NP_478108