IFT122 antibody

Catalog No. ABIN2463614

Product Details anti-IFT122 Antibody

Target: IFT122 (Intraflagellar Transport 122 (IFT122))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFT122 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IFT122.

Application Details

Application Notes: IFT122 antibody can be used for detection of IFT122 by ELISA at 1:1562500. IFT122 antibody can be used for detection of IFT122 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store IFT122 antibody at -20 °C.

Target Details for IFT122

Target: IFT122 (Intraflagellar Transport 122 (IFT122))

Alternative Name: IFT122 (IFT122 Products)

Synonyms: C86139 antibody, Wdr10 antibody, sopb antibody, CED antibody, CED1 antibody, SPG antibody, WDR10 antibody, WDR10p antibody, WDR140 antibody, intraflagellar transport 122 antibody, intraflagellar transport protein 122 homolog antibody, IFT122 antibody, ift122 antibody, LOC100639275 antibody, LOC100649523 antibody, Ift122 antibody

Background: IFT122 is a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. IFT122 contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation.This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight: 129 kDa

Gene ID: 55764

NCBI Accession: NP_443716

UniProt: Q9HBG6

Pathways: Tube Formation, Embryonic Body Morphogenesis