SUB1 antibody
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- Target See all SUB1 Antibodies
- SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
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Reactivity
- Human, Mouse, Rat, Dog, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SUB1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Antibody is supplied as total IgG.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PC4.
- Top Product
- Discover our top product SUB1 Primary Antibody
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- Application Notes
- PC4 antibody can be used for detection of PC4 by ELISA at 1:7812500. PC4 antibody can be used for detection of PC4 by western blot at 0.5-1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 200 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PC4 antibody at -20 °C.
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- Target
- SUB1 (Activated RNA Polymerase II Transcriptional Coactivator p15 (SUB1))
- Alternative Name
- PC4 (SUB1 Products)
- Synonyms
- P15 antibody, PC4 antibody, p14 antibody, AI842364 antibody, P9 antibody, Pc4 antibody, Rpo2tc1 antibody, SUB1 homolog, transcriptional regulator antibody, SUB1 homolog (S. cerevisiae) antibody, SUB1 antibody, Sub1 antibody
- Background
- PC4 (activated RNA polymerase II transcription cofactor 4) is a transcriptional coactivator, possessing the ability to suppress promoter-driven as well as nonspecific transcription via its DNA binding activity. The repressive activity of PC4 on promoter-driven transcription is alleviated by transcription factor TFIIH. TFIIH protects promoters from PC4-mediated repression by relieving the topological constraint imposed by PC4 through the ERCC3 helicase activity.
- Molecular Weight
- 14 kDa
- Gene ID
- 10923
- NCBI Accession
- NP_006704
- UniProt
- P53999
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