Claudin 18 antibody

Catalog No. ABIN2463897

Product Details anti-Claudin 18 Antibody

Target: Claudin 18 (CLDN18)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 18 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CLDN18.

Application Details

Application Notes: CLDN18 antibody can be used for detection of CLDN18 by ELISA at 1:62500. CLDN18 antibody can be used for detection of CLDN18 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CLDN18 antibody at -20 °C.

Target Details for Claudin 18

Target: Claudin 18 (CLDN18)

Alternative Name: CLDN18 (CLDN18 Products)

Synonyms: claudin-18 antibody, CLDN18 antibody, SFTA5 antibody, SFTPJ antibody, claudin 18 L homeolog antibody, claudin 18 antibody, cldn18.L antibody, CLDN18 antibody, Cldn18 antibody

Background: CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells (Niimi et al., 2001 [PubMed 11585919]).

Molecular Weight: 28 kDa

Gene ID: 51208

NCBI Accession: NP_057453

UniProt: P56856

Pathways: Cell-Cell Junction Organization, Hepatitis C