TRIM27 antibody

Catalog No. ABIN2463902

Product Details anti-TRIM27 Antibody

Target: TRIM27 (Tripartite Motif Containing 27 (TRIM27))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM27 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TRIM27.

Application Details

Application Notes: TRIM27 antibody can be used for detection of TRIM27 by ELISA at 1:1562500. TRIM27 antibody can be used for detection of TRIM27 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TRIM27 antibody at -20 °C.

Target Details for TRIM27

Target: TRIM27 (Tripartite Motif Containing 27 (TRIM27))

Alternative Name: TRIM27 (TRIM27 Products)

Synonyms: RFP antibody, RNF76 antibody, AW538890 antibody, Gm19403 antibody, Rfp antibody, TRIM27 antibody, Rfp1 antibody, tripartite motif containing 27 antibody, tripartite motif-containing 27 antibody, TRIM27 antibody, Trim27 antibody

Background: TRIM27 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the nuclear matrix. It interacts with the enhancer of polycomb protein and represses gene transcription. It is also thought to be involved in the differentiation of male germ cells. Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein.

Molecular Weight: 41 kDa

Gene ID: 5987

NCBI Accession: NP_112212

UniProt: P14373