MGAT2 antibody

Catalog No. ABIN2463976

Product Details anti-MGAT2 Antibody

Target: MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MGAT2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MGAT2.

Application Details

Application Notes: MGAT2 antibody can be used for detection of MGAT2 by ELISA at 1:62500. MGAT2 antibody can be used for detection of MGAT2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MGAT2 antibody at -20 °C.

Target Details for MGAT2

Target: MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))

Alternative Name: MGAT2 (MGAT2 Products)

Synonyms: CDG2A antibody, CDGS2 antibody, GLCNACTII antibody, GNT-II antibody, GNT2 antibody, CG7921 antibody, Dmel\\CG7921 antibody, GlcNAc-TII antibody, GlcNAcT2 antibody, dMGAT2 antibody, MGC89475 antibody, Gnt2 antibody, AA407964 antibody, CH73-301C19.1 antibody, zgc:162268 antibody, mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase antibody, CG7921 gene product from transcript CG7921-RB antibody, mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase L homeolog antibody, mannoside acetylglucosaminyltransferase 2 antibody, MGAT2 antibody, Mgat2 antibody, mgat2.L antibody, mgat2 antibody

Background: MGAT2 is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in its gene may lead to carbohydrate-deficient glycoprotein syndrome, type II.The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. Two transcript variants encoding the same protein have been identified for this gene.

Molecular Weight: 51 kDa

Gene ID: 4247

NCBI Accession: NP_002399

UniProt: Q10469