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Lipase A antibody (truncated)

LIPA Reactivity: Human WB, ELISA Host: Mouse Monoclonal 9G7F12 unconjugated
Catalog No. ABIN2464075
  • Target See all Lipase A (LIPA) Antibodies
    Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))
    Binding Specificity
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    truncated
    Reactivity
    • 28
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 23
    • 5
    • 1
    Mouse
    Clonality
    • 25
    • 5
    Monoclonal
    Conjugate
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Lipase A antibody is un-conjugated
    Application
    • 24
    • 12
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purification
    Antibody is purified by protein A affinity chromatography.
    Immunogen
    Ni-NTA purified truncated recombinant LAL expressed in E. Coli strain BL21 (DE3).
    Clone
    9G7F12
    Isotype
    IgG2a
    Top Product
    Discover our top product LIPA Primary Antibody
  • Application Notes
    Western Blot:Dilution 1:500 - 1:2,000
    ELISA:Propose dilution 1:10,000.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Buffer
    Purified antibody in PBS containing 0.03 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
    Storage
    -20 °C
    Storage Comment
    LAL monoclonal antibody can be stored at -20 °C, stable for one year.
  • Target
    Lipase A (LIPA) (Lipase A, Lysosomal Acid, Cholesterol Esterase (LIPA))
    Alternative Name
    LAL (LIPA Products)
    Synonyms
    cesd antibody, lal antibody, LIPA antibody, CESD antibody, LAL antibody, Chole antibody, Chole2 antibody, Lip1 antibody, AA960673 antibody, Lal antibody, Lip-1 antibody, lipase A, lysosomal acid type antibody, lipase A, lysosomal acid, cholesterol esterase antibody, lipase A, lysosomal acid, cholesterol esterase L homeolog antibody, lysosomal acid lipase A antibody, LIPA antibody, lipa antibody, lipa.L antibody, Lipa antibody
    Background
    Lysosomal acid lipase (LAL), with 378-amino acid protein( 43-54 kDa), functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides which are taken up by receptor-mediated endocytosis. An inherited deficiency or low activity of human lysosomal acid lipase results in the intralysosomal storage of the respective lipid substrates. So it is also responsible for the rare conditions of Wolman disease and cholesteryl ester storage disease (CESD). As the enzyme is synthesized by all nucleated cells, lipid-laden cells are found in all organs, particularly in liver, spleen, the adrenal and the hemopoietic system, and in the intestine as well as in the lymph nodes, lungs, testes, and ovaries.
    Gene ID
    3988
    UniProt
    P38571
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