SRP54 antibody (AA 300-504)

Catalog No. ABIN2467892

Product Details anti-SRP54 Antibody

Target: SRP54 (Signal Recognition Particle 54kDa (SRP54))

Binding Specificity: AA 300-504

Reactivity: Human, Mouse, Rat

Host: Chicken

Clonality: Polyclonal

Conjugate: This SRP54 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity-purified

Application Details

Application Notes: SRP54 antibody can be used for the detection of SRP54 by Western blot, may also work for IHC and ICC.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Preservative: Without preservative

Handling Advice: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Storage: 4 °C/-20 °C

Storage Comment: SRP54 antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Target Details for SRP54

Target: SRP54 (Signal Recognition Particle 54kDa (SRP54))

Alternative Name: SRP54 (SRP54 Products)

Synonyms: Srp54k antibody, zgc:55842 antibody, zgc:85713 antibody, SRP54 antibody, signal recognition particle 54 antibody, signal recognition particle protein antibody, signal recognition particle subunit Srp54 antibody, signal recognition particle antibody, family with sequence similarity 177 member A1 antibody, signal recognition particle 54kDa S homeolog antibody, signal recognition particle 54kDa antibody, SRP54 antibody, srp54 antibody, SSO_RS04840 antibody, MA_RS23935 antibody, AF_RS03170 antibody, PAB_RS02540 antibody, MSP_RS07670 antibody, RCI_RS04175 antibody, TGAM_RS09885 antibody, MTBMA_RS08340 antibody, FAM177A1 antibody, srp54.S antibody, Srp54 antibody

Background: Human signal recognition particle 54 kDa. The signal recognition particle (SRP) is an oligomeric complex that mediates targeting and insertion of the signal sequence of exported proteins into the membrane of the endoplasmic reticulum. SRP consists of a 7S RNA and six protein subunits. 54 kD protein (SRP54) is one of these subunits. It is a GTP-binding protein that interacts with the signal sequence when it emerges from the ribosome. The 54K subunit of the signal recognition particle has a two domain structure: the G-domain that binds GTP and the M-domain that binds the 7s RNA and also binds the signal sequence. The N-terminal 300 residues of SRP54 include the GTP-binding site (G-domain) and are evolutionary related to similar domains in other proteins.

Molecular Weight: 55.7 kDa (calculated)

Gene ID: 6729

NCBI Accession: NP_003127

UniProt: P61011

Pathways: SARS-CoV-2 Protein Interactome