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DDR1 antibody (N-Term)
DDR1
Reactivity: Human, Monkey, Chimpanzee, Gorilla, Gibbon
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DDR1 Antibody
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Target
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DDR1
(Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
Binding Specificity
All epitopes for DDR1 antibodies
N-Term
Reactivity
All reactivities for DDR1 antibodies
Human, Monkey, Chimpanzee, Gorilla, Gibbon
Host
All hosts for DDR1 antibodies
Rabbit
Clonality
All clonalities for DDR1 antibodies
Polyclonal
Conjugate
All conjugates for DDR1 antibodies
This DDR1 antibody is un-conjugated
Application
All applications for DDR1 antibodies
Immunohistochemistry (IHC)
Specificity
BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purification
Immunoaffinity Chromatography
Immunogen
DDR1 antibody was raised against a peptide located in the N-Terminal region of DDR1 (Human).
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Alternatives
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Application Details
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Application Notes
DDR1 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 20 μg/mL.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS, 0.1 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
As with all antibodies avoid freeze/thaw cycles.
Storage
4 °C/-80 °C
Storage Comment
DDR1 antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.
Target Details for DDR1
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Target
DDR1
(Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))
Alternative Name
DDR1 (DDR1 Products )
Synonyms
CG11573 antibody, CG13984 antibody, CG13985 antibody, CG33531 antibody, CG9488 antibody, CG9490 antibody, CT33540 antibody, DDR antibody, Dmel\\CG33531 antibody, Dmel_CG13984 antibody, 6030432F18 antibody, AI323681 antibody, CD167a antibody, Cak antibody, Nep antibody, PTK3A antibody, CAK antibody, CD167 antibody, EDDR1 antibody, HGK2 antibody, MCK10 antibody, NEP antibody, NTRK4 antibody, PTK3 antibody, RTK6 antibody, TRKE antibody, Drd1 antibody, PTK3D antibody, Discoidin domain receptor antibody, discoidin domain receptor family, member 1 antibody, discoidin domain receptor tyrosine kinase 1 antibody, Ddr antibody, Ddr1 antibody, DDR1 antibody
Background
DDR1 is a DDR/TKT type protein kinase. DDR1 is activated by various types of collagen, including types I through IV. Binding of collagen to DDR1 protein results in autophosphorylation and a delayed but sustained tyrosine kinase activation. DDR1 may function in cell-to-cell interaction or recognition. At least three mRNA variants, resulting in different protein isoforms of 875, 913 and 919 amino acids, have been reported. DDR1 protein has been shown to be over expressed in human breast, ovarian, esophageal and pediatric brain tumors.
Gene ID
780
UniProt
Q08345
Pathways
RTK Signaling , Smooth Muscle Cell Migration
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