Oxytocin Receptor antibody (C-Term)

Catalog No. ABIN2469371

Product Details anti-Oxytocin Receptor Antibody

Target: Oxytocin Receptor (OXTR)

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Oxytocin Receptor antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: Oxytocin Receptor antibody was raised against a peptide located in the C-Terminal cytoplasmic domain of Oxytocin Receptor (Human).

Application Details

Application Notes: Oxytocin Receptor antibody can be used in immunohistochemistry starting at 8 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: Oxytocin Receptor antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for Oxytocin Receptor

Target: Oxytocin Receptor (OXTR)

Alternative Name: Oxytocin Receptor (OXTR Products)

Synonyms: OXTR antibody, OT-R antibody, OTR antibody, OTR1 antibody, oxytocin receptor antibody, OXTR antibody, Oxtr antibody

Background: The oxytocin receptor belongs to the vasopressin/oxytocin family of GPCRs because it binds similar cyclic nonapeptide hormones. The oxytocin receptor functions primarily during labor and lactation. There is a dramatic increase in the number of oxytocin receptors just before the onset of labor causing the uterine muscles to become exceedingly sensitive to oxytocin. The activated oxytocin receptor causes an inward membrane current that results in smooth muscle contraction during labor and milk ejection during lactation. This receptor also plays a role in natriuresis, kaliuresis and may have an antistress effect.

Gene ID: 5021

UniProt: P30559

Pathways: Myometrial Relaxation and Contraction, Feeding Behaviour