CERK antibody (Internal Region)

Catalog No. ABIN2469403

Product Details anti-CERK Antibody

Target: CERK (Ceramide Kinase (CERK))

Binding Specificity: Internal Region

Reactivity: Human, Monkey, Gibbon

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CERK antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Specificity: BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Immunoaffinity Chromatography

Immunogen: Ceramide Kinase antibody was raised against a peptide located near the internal domain of Ceramide Kinase (Human).

Application Details

Application Notes: Ceramide Kinase antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-80 °C

Storage Comment: Ceramide Kinase antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Target Details for CERK

Target: CERK (Ceramide Kinase (CERK))

Alternative Name: Ceramide Kinase (CERK Products)

Synonyms: AI848610 antibody, D330016D08Rik antibody, mKIAA1646 antibody, LK4 antibody, dA59H18.2 antibody, dA59H18.3 antibody, hCERK antibody, CERK antibody, si:ch211-162i19.1 antibody, MGC81777 antibody, CG16708 antibody, DCERK antibody, Dcerk antibody, Dmel\\CG16708 antibody, dcerk antibody, ceramide kinase antibody, ceramide kinase S homeolog antibody, Ceramide kinase antibody, Cerk antibody, CERK antibody, cerk antibody, cerk.S antibody, CpipJ_CPIJ003342 antibody, LOAG_11245 antibody, LOC5579301 antibody, Bm1_50005 antibody

Background: CERK, which phosphorylates Cer to produce ceramide 1-phosphate (C1P), was initially described as a Ca2+-stimulated lipid kinase that copurified with brain synaptic vesicles. CERK activity has been reported in HL60 cells, mast cells, and neutrophils. CERK is involved in phagolysosome formation in polymorphonuclear leukocytes and also in liposome fusion. C1P has been reported to have mitogenic effects. More recently, C1P was found to induce arachidonic acid release and prostanoid synthesis.

Gene ID: 64781

UniProt: Q8TCT0