RAMP3 antibody (N-Term)

Catalog No. ABIN2469865

Product Details anti-RAMP3 Antibody

Target: RAMP3 (Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAMP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunoaffinity Chromatography

Immunogen: RAMP3 antibody was raised against a synthetic peptide corresponding to N-Terminal residues of RAMP3 (Human).

Application Details

Application Notes: RAMP3 antibody can be used in ELISA starting at 1:3000 - 1:6000, Western Blot starting at 1:3000 - 1:6000, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.01 % sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: As with all antibodies avoid freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store RAMP3 antibody at 4 °C or -20 °C.

Target Details for RAMP3

Target: RAMP3 (Receptor (G Protein-Coupled) Activity Modifying Protein 3 (RAMP3))

Alternative Name: RAMP3 (RAMP3 Products)

Synonyms: RAMP3 antibody, ramp3 antibody, AI850306 antibody, receptor activity modifying protein 3 antibody, receptor (G protein-coupled) activity modifying protein 3 antibody, Receptor activity-modifying protein 3 antibody, receptor (calcitonin) activity modifying protein 3 antibody, RAMP3 antibody, ramp3 antibody, Ramp3 antibody

Background: RAMP3 is a member of the RAMP family of single-transmembrane-domain proteins, called receptor-activity-modifying proteins. RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. Co-expression of RAMP3 with CRLR results in the production of a functional adrenomedullin receptor.

Gene ID: 10268

UniProt: O60896

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling