Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

TLX1 antibody (AA 300-330)

TLX1 Reactivity: Mouse, Human, Rat, Rabbit, Cow, Dog, Monkey, Bat, Horse, Chicken, Hamster, Gibbon, Gorilla WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2470149
  • Target See all TLX1 Antibodies
    TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))
    Binding Specificity
    • 15
    • 8
    • 8
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 300-330
    Reactivity
    • 39
    • 29
    • 8
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Mouse, Human, Rat, Rabbit, Cow, Dog, Monkey, Bat, Horse, Chicken, Hamster, Gibbon, Gorilla
    Host
    • 41
    Rabbit
    Clonality
    • 41
    Polyclonal
    Conjugate
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TLX1 antibody is un-conjugated
    Application
    • 41
    • 16
    • 13
    • 13
    • 8
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Purification
    Protein G Column
    Immunogen
    TLX1 antibody was raised against amino acids 300 - 330 of TLX1 (Human).
    Isotype
    IgG
    Top Product
    Discover our top product TLX1 Primary Antibody
  • Application Notes
    TLX1 antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, 0.2 % gelatin, 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    As with all antibodies avoid freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    TLX1 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.
  • Target
    TLX1 (T-Cell Leukemia Homeobox 1 (TLX1))
    Alternative Name
    TLX1 (TLX1 Products)
    Synonyms
    Hox-11 antibody, Hox11 antibody, HOX11 antibody, TCL3 antibody, XHox11 antibody, XHox11L2 antibody, hox11 antibody, tlx1-a antibody, TLX-1 antibody, RGD1563655 antibody, SI:dZ46P4.1 antibody, Tlx-1 antibody, ztlx-1 antibody, T cell leukemia, homeobox 1 antibody, T-cell leukemia homeobox 1 antibody, T-cell leukemia homeobox 1 L homeolog antibody, T-cell leukemia, homeobox 1 antibody, Tlx1 antibody, TLX1 antibody, tlx1.L antibody, tlx1 antibody
    Background
    HOX11, also called homeobox11 or Tcl-3 is located at the 10q24 T-Cell translocation breakpoint region. It encodes a homeobox-domain containing protein, HOX11, containing a glycine and proline-rich amino terminus. HOX11 is required for maintenance of the developing spleen and cell survival. The HOX11protein binds to a specific DNA sequence and localizes to the cell nucleus. It transactivates transcription of a reporter gene linked to a cis-regulatory element, acting as a positive transcription activator. The HOX11 gene is highly expressed in T-ALLs as a result of a t (7:10) (q35,q24) or t(10:14)(q24,qll) translocation. The homeobox gene is deregulated upon translocation into the T-cell receptor locus and activates a specific subset of tumor-associated target genes. HOX 11 gene translocation has been attributed to T-cell leukemia and lymphoid neoplasias.
    Gene ID
    3195
    UniProt
    P31314
You are here:
Support