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SPRY4 antibody (AA 306-322)

SPRY4 Reactivity: Human, Chimpanzee WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2470367
  • Target See all SPRY4 Antibodies
    SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))
    Binding Specificity
    • 10
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 306-322
    Reactivity
    • 58
    • 12
    • 11
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Chimpanzee
    Host
    • 58
    Rabbit
    Clonality
    • 57
    • 1
    Polyclonal
    Conjugate
    • 22
    • 7
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPRY4 antibody is un-conjugated
    Application
    • 39
    • 38
    • 17
    • 12
    • 7
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Immunoaffinity Chromatography
    Immunogen
    SPRY4 antibody was raised against amino acids 306-322 of SPRY4 (Human).
    Top Product
    Discover our top product SPRY4 Primary Antibody
  • Application Notes
    SPRY4 antibody can be used in Western Blot, immunohistochemistry starting at 1:200, and immunoprecipitation.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    As with all antibodies avoid freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store SPRY4 antibody at 4 °C or -20 °C.
  • Target
    SPRY4 (Sprouty RTK Signaling Antagonist 4 (SPRY4))
    Alternative Name
    SPRY4 (SPRY4 Products)
    Synonyms
    SPRY4 antibody, LOC100218545 antibody, HH17 antibody, A030006O18Rik antibody, sprouty4 antibody, sprouty RTK signaling antagonist 4 antibody, sprouty (Drosophila) homolog 4 antibody, sprouty homolog 4 (Drosophila) antibody, Spry4 antibody, SPRY4 antibody, spry4 antibody
    Background
    Sprouty-4 (also known as SPRY4) is an inhibitor of the insulin receptor and EGFR-transduced mitogen-activated protein kinase (MAPK) signaling pathway downstream of FGF and EGF receptor tyrosine kinase activation. It is positioned upstream of RAS activation and impairs the formation of active GTP-RAS. SPRY4 is widely expressed, with different isoforms. The protein consists of 322 amino acids, with a cysteine-rich region, Src homology 3 binding regions, proline-rich regions, and a PEST sequence. It is expressed predominantly in the cytoplasm. Northern results show bands across most tissues, with strongest expression in heart, brain, placenta, lung, and intestine.
    Gene ID
    81848
    UniProt
    Q9C004
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