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CDK2 antibody

CDK2 Reactivity: Human, Mouse, Xenopus laevis WB, IHC, ELISA, IP Host: Mouse Monoclonal unconjugated
Catalog No. ABIN2470565
  • Target See all CDK2 Antibodies
    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
    Reactivity
    • 179
    • 96
    • 77
    • 10
    • 10
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    Human, Mouse, Xenopus laevis
    Host
    • 185
    • 19
    • 1
    Mouse
    Clonality
    • 172
    • 33
    Monoclonal
    Conjugate
    • 99
    • 19
    • 15
    • 10
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    This CDK2 antibody is un-conjugated
    Application
    • 173
    • 76
    • 52
    • 49
    • 49
    • 39
    • 34
    • 25
    • 20
    • 13
    • 10
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
    Specificity
    Recognizes cdk2, Mr 33kD. Does not cross-react with other cdks.
    Purification
    Protein G Column
    Immunogen
    CDK2 monoclonal antibody was raised against recombinant CDK2 (Human).
    Isotype
    IgG
    Top Product
    Discover our top product CDK2 Primary Antibody
  • Application Notes
    CDK2 antibody can be used in immunohistochemistry starting at 10 μg/mL.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05 % sodium azide, before the addition of glycerol to 30 %
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    As with all antibodies avoid freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store CDK2 antibody at 4 °C or -20 °C.
  • Target
    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))
    Alternative Name
    CDK2 (CDK2 Products)
    Synonyms
    p33(CDK2) antibody, A630093N05Rik antibody, wu:fa10c02 antibody, zgc:56598 antibody, zgc:77684 antibody, eg1 antibody, CDKN2 antibody, cdk2L antibody, cyclin dependent kinase 2 antibody, cyclin-dependent kinase 2 antibody, cyclin-dependent kinase 2 S homeolog antibody, CDK2 antibody, Cdk2 antibody, cdk2 antibody, cdk2.S antibody
    Background
    Cyclin-dependent kinase 2 (CDK2), a CDC2/CDK-type protein kinase, regulates cell-cycle transition from G1 to S phase. CDK2 activation requires formation of a heterodimer with cyclin A, D, or E and phosphorylation by CAK. CDK2 inhibition results from association with p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Two alternatively spliced variants and multiple transcription initiation sites have been reported. Inhibition of CDK2 has been suggested to help prevent chemotherapy-induced alopecia in cancer patients.
    Gene ID
    1017
    UniProt
    P24941
    Pathways
    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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