NFKBIA antibody (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha) (C-Term)

Details for Product anti-NFKBIA Antibody No. ABIN2475865, Supplier: Log in to see
Antigen
  • AI462015
  • Nfkbi
  • IKBA
  • MAD-3
  • NFKBI
  • ECI-6/IKBA
  • RL/IF-1
  • nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
  • nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
  • NFKBIA
  • LOC100220015
  • LOC100357341
  • Nfkbia
Alternatives
anti-Human NFKBIA antibody for Western Blotting
Epitope
C-Term
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Reactivity
Human, Mouse (Murine), Rat (Rattus)
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29
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2
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Host
Rabbit
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Clonality
Polyclonal
Conjugate
This NFKBIA antibody is un-conjugated
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Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), ELISA, Western Blotting (WB)
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Options
Supplier
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Supplier Product No.
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Immunogen NFkBIa peptide corresponding to a region near the C-terminus of the human protein, conjugated with KLH.
Isotype IgG
Specificity This antibody is specific for NF-kappa-B inhibitor alpha (also known as IkB alpha), one of seven members of the IkB class of inhibitor proteins that have been identified to date. NFkBIa inhibits the NFkB complex in unstimulated cells through non-covalent binding. Following stimulation of cells, IkB alpha is phosphorylated so that it dissociates from the NFkB, and then ubiquinated prior to degradation.
Cross-Reactivity Mouse (Murine), Rat (Rattus)
Characteristics Serum
Alternative Name NF kappa B INHIBITOR alpha (NFKBIA Antibody Abstract)
Background Synonyms: IkB ALPHA
Gene ID 4792
UniProt P25963
Pathways NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Maintenance of Protein Location, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 80.0 mg/mL
Product cited in: Hoffmann, Levchenko, Scott, Baltimore: "The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation." in: Science (New York, N.Y.), Vol. 298, Issue 5596, pp. 1241-5, 2002 (PubMed).

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