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Biliverdin Reductase antibody (FITC)

BLVRA Reactivity: Human WB, IHC, IP, ICC, IF Host: Rabbit Polyclonal FITC
Catalog No. ABIN2482003
  • Target See all Biliverdin Reductase (BLVRA) Antibodies
    Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))
    Reactivity
    • 65
    • 30
    • 18
    Human
    Host
    • 72
    • 6
    Rabbit
    Clonality
    • 74
    • 4
    Polyclonal
    Conjugate
    • 22
    • 7
    • 6
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Biliverdin Reductase antibody is conjugated to FITC
    Application
    • 48
    • 31
    • 26
    • 19
    • 18
    • 16
    • 15
    • 13
    • 13
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    Detects ~40-42 kDa.
    Cross-Reactivity
    Human
    Purification
    Protein A Purified
    Immunogen
    Human native full-length BVR
    Top Product
    Discover our top product BLVRA Primary Antibody
  • Application Notes
    • WB (1:2000)
    • ICC/IF (1:120)
    • IP (1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    1 μg/ml of ABIN2482003 was sufficient for detection of BVR in 10 μg of mixed human cell line lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))
    Alternative Name
    BVR (BLVRA Products)
    Synonyms
    blvra antibody, MGC69310 antibody, BLVRA antibody, zgc:153046 antibody, BVR antibody, Dmel\\CG9471 antibody, BLVR antibody, BVRA antibody, 0610006A11Rik antibody, 2500001N03Rik antibody, Blvr antibody, biliverdin reductase A antibody, biliverdin reductase A L homeolog antibody, CG9471 gene product from transcript CG9471-RA antibody, BLVRA antibody, blvra antibody, blvra.L antibody, CG9471 antibody, Blvra antibody
    Background
    Biliverdin Reductase (BVR) is a cytoplasmic enzyme that catalyzes the conversion of biliverdin to bilirubin by converting a double bond between the second and third pyrrole ring into a single bond (1). It is ubiqutiously expressed in all tissues- it occurs in cells and brain regiuons that already display HO-1 and HO-2, but also in regions and cell types with potential to induce stress proteins. It is unique among all enzymes in having two pH optima, using a different cofactor at each pH range, NADH at pH 7.0 and NADPH at pH 8.7 (2). It is not inactivated by heat shock, and have shown to abate inflammation, oxidative stress and apoptosis (3).
    Gene ID
    644
    NCBI Accession
    NP_000703
    UniProt
    P53004
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