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DICER1 antibody (AA 1638-1899) (Alkaline Phosphatase (AP))

DICER1 Reactivity: Mouse WB, ICC, IF Host: Mouse Monoclonal S167-7 Alkaline Phosphatase (AP)
Catalog No. ABIN2483010
  • Target See all DICER1 Antibodies
    DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
    Binding Specificity
    • 15
    • 11
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1638-1899
    Reactivity
    • 49
    • 22
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 39
    • 23
    • 1
    Mouse
    Clonality
    • 39
    • 24
    Monoclonal
    Conjugate
    • 36
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DICER1 antibody is conjugated to Alkaline Phosphatase (AP)
    Application
    • 51
    • 17
    • 16
    • 13
    • 13
    • 13
    • 13
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    Detects ~215 kDa.
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Protein G Purified
    Immunogen
    Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer
    Clone
    S167-7
    Isotype
    IgG1
    Top Product
    Discover our top product DICER1 Primary Antibody
  • Application Notes
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    1 μg/ml of ABIN2483010 was sufficient for detection of Dicer in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
    Alternative Name
    Dicer (DICER1 Products)
    Synonyms
    dcr1 antibody, dicer antibody, herna antibody, DICER1 antibody, dicer1 antibody, 1110006F08Rik antibody, D12Ertd7e antibody, mKIAA0928 antibody, DCR1 antibody, Dicer antibody, HERNA antibody, MNG1 antibody, DICER antibody, fc39d11 antibody, fc74b05 antibody, wu:fc39d11 antibody, wu:fc74b05 antibody, dicer 1, ribonuclease III antibody, endoribonuclease Dicer antibody, dicer 1, ribonuclease III S homeolog antibody, dicer 1, ribonuclease type III antibody, dicer 1 ribonuclease III antibody, DICER1 antibody, CpipJ_CPIJ010534 antibody, dicer1 antibody, dicer1.S antibody, Dicer1 antibody
    Background
    Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) (1). After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha (2), pre-miRNAs are transported to the cytoplasm and further processed by Dicer to produce 22-nucleotide mature miRNAs (3). The mature miRNA then becomes a part of the RNA-Induced Silencing Complex (RISC) and can bind to the 3' UTR of the target mRNA (3)
    Gene ID
    192119
    NCBI Accession
    NP_683750
    UniProt
    Q8R418
    Pathways
    Regulatory RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization
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