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ASIC1 antibody (AA 460-526) (FITC)

ACCN2 Reactivity: Mouse WB, IHC, ICC, IF Host: Mouse Monoclonal S271-44 FITC
Catalog No. ABIN2483693
  • Target See all ASIC1 (ACCN2) Antibodies
    ASIC1 (ACCN2) (Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))
    Binding Specificity
    • 15
    • 13
    • 13
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 460-526
    Reactivity
    • 76
    • 68
    • 42
    • 12
    • 11
    • 6
    • 6
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Mouse
    Host
    • 75
    • 15
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 78
    • 15
    Monoclonal
    Conjugate
    • 31
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ASIC1 antibody is conjugated to FITC
    Application
    • 87
    • 36
    • 26
    • 16
    • 16
    • 15
    • 13
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    Detects ~60 kDa.
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Protein G Purified
    Immunogen
    Fusion protein amino acids 460-526 (Cytoplasmic C-terminus) of mouse ASIC1
    Clone
    S271-44
    Isotype
    IgG1
    Top Product
    Discover our top product ACCN2 Primary Antibody
  • Application Notes
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    Comment

    1 μg/ml of ABIN2483693 was sufficient for detection of ASIC1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    ASIC1 (ACCN2) (Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))
    Alternative Name
    ASIC1 (ACCN2 Products)
    Synonyms
    ACCN2 antibody, ASIC antibody, BNaC2 antibody, Accn2 antibody, ASIC1 antibody, AI843610 antibody, ASIC1a antibody, B530003N02Rik antibody, acid sensing ion channel subunit 1 antibody, acid-sensing (proton-gated) ion channel 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 antibody, ASIC1 antibody, Asic1 antibody, asic1 antibody, SMARCD1 antibody
    Background
    Acid sensing ion channel ASIC1, also designated ACCN2, BNAC2 and ASIC1a, is present in brain as a 4.3-kb transcript with localization to rat dorsal root ganglia. Insitu hybridization of rat brain suggests that ASIC1 is most abundant in the main olfactory bulb, cerebral cortex, hippocampal formation, habenula, basolateral amygdaloid nuclei and cerebellum. ASIC1 and H+-gated currents may contribute to the development of fear and anxiety.
    Gene ID
    11419
    NCBI Accession
    NP_033727
    UniProt
    Q6NXK8
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