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NPAS4 antibody (AA 597-802) (APC)

NPAS4 Reactivity: Rat WB, IHC, IF, ICC Host: Mouse Monoclonal S408-79 APC
Catalog No. ABIN2485816
  • Target See all NPAS4 Antibodies
    NPAS4 (Neuronal PAS Domain Protein 4 (NPAS4))
    Binding Specificity
    • 10
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 597-802
    Reactivity
    • 25
    • 20
    • 18
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Rat
    Host
    • 25
    • 11
    • 1
    Mouse
    Clonality
    • 26
    • 11
    Monoclonal
    Conjugate
    • 16
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NPAS4 antibody is conjugated to APC
    Application
    • 23
    • 17
    • 14
    • 14
    • 13
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Highly expressed in the brain, with lower expression found in endocrine tissue.,Detects ~90 kDa.
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Protein G Purified
    Immunogen
    Fusion protein amino acids 597-802 (C-terminus) of rat Npas4.
    Clone
    S408-79
    Isotype
    IgG1
    Top Product
    Discover our top product NPAS4 Primary Antibody
  • Application Notes
    • WB (1:1000)
    • ICC/IF(1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    A 1:100 dilution of ABIN2485816 was sufficient for detection of NPAS4 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    NPAS4 (Neuronal PAS Domain Protein 4 (NPAS4))
    Alternative Name
    NPAS4 (NPAS4 Products)
    Synonyms
    LE-PAS antibody, Nxf antibody, Le-PAS antibody, NXF antibody, PASD10 antibody, bHLHe79 antibody, npas4 antibody, wu:fj52d04 antibody, zgc:136764 antibody, MGC146621 antibody, neuronal PAS domain protein 4 antibody, neuronal PAS domain protein 4a antibody, neuronal PAS domain-containing protein 4 antibody, Npas4 antibody, NPAS4 antibody, npas4a antibody, npas4 antibody, Tsp_02837 antibody
    Background
    NPAS4 belongs to the Per-Arnt-Sim family of neuronal specific transciption factors, all involved in the development and maintenance of learning and memory pathways (1). NPAS4 is a transcription factor that regulates the formation and maintenance of inhibitory synapses, and can activate the CNS midline enhancer element and the expression of the drebrin gene. Deregulation has been to be associated with developmental disorders such as schizophrenia and autism (2).
    Gene ID
    266734
    NCBI Accession
    NP_705890
    UniProt
    Q8CJH6
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