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Aquaporin 1 antibody (N-Term) (Biotin)

AQP1 Reactivity: Rat WB, IHC, IF, ICC Host: Rabbit Polyclonal Biotin
Catalog No. ABIN2486444
  • Target See all Aquaporin 1 (AQP1) Antibodies
    Aquaporin 1 (AQP1) (Aquaporin 1 (Colton Blood Group) (AQP1))
    Binding Specificity
    • 18
    • 16
    • 12
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 93
    • 68
    • 62
    • 5
    • 5
    • 2
    • 2
    Rat
    Host
    • 99
    • 9
    • 2
    Rabbit
    Clonality
    • 91
    • 19
    Polyclonal
    Conjugate
    • 48
    • 11
    • 9
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Aquaporin 1 antibody is conjugated to Biotin
    Application
    • 85
    • 43
    • 42
    • 25
    • 19
    • 18
    • 17
    • 16
    • 14
    • 13
    • 9
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Detects ~28.5 kDa. May detect larger glycosylated bands ~35-50 kDa.
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Protein A Purified
    Immunogen
    Produced against the N-terminal peptide (sequence N-MASEFKKKLF) of rat Aquaporin 1
    Top Product
    Discover our top product AQP1 Primary Antibody
  • Application Notes
    • WB (1:2000)
    • IHC (1:200)
    • ICC/IF (1:400)
    • optimal dilutions for assays should be determined by the user.
    Comment

    0.5 μg/ml of ABIN2486444 was sufficient for detection of aquaporin 1 in 10 μg of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Conjugated antibodies should be stored at 4°C
  • Target
    Aquaporin 1 (AQP1) (Aquaporin 1 (Colton Blood Group) (AQP1))
    Alternative Name
    Aquaporin 1 (AQP1 Products)
    Synonyms
    fj33g04 antibody, zgc:85890 antibody, wu:fj33g04 antibody, AQP1 antibody, CHIP28 antibody, AQP-CHIP antibody, CO antibody, AQP-1 antibody, CHIP29 antibody, aquaporin 1a (Colton blood group), tandem duplicate 1 antibody, aquaporin 1 antibody, aquaporin 1 (Colton blood group) antibody, aqp1a.1 antibody, AQP1 antibody, Aqp1 antibody
    Background
    Aquaporins selectively conduct water molecules in and out of the cell, while preventing the passage of ions and other solutes. Known as water channels, they are integral membrane pore proteins (1, 2). Aquarporin 1 is a widely expressed water channel, found in the basolateral and apical plasma membranes of the proximal tubes, the descending loop of Henel and in the descending portion of the vasa recta. Additionally it is found in red blood cells, vascular endothelium, gastrointestinal tract, sweat glands and lungs. It is not regulated by vasopressin (3).
    Gene ID
    25240
    NCBI Accession
    NP_036910
    UniProt
    P29975
    Pathways
    Hormone Transport
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