25(OH)Vitamin D3-1-alpha-Hydroxylase antibody

Antigen: 25(OH)Vitamin D3-1-alpha-Hydroxylase

Clonality: Polyclonal

Host: Sheep

Reactivity: Mouse (Murine), Human

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Catalog no.: ABIN249304

Additional Information

Immunogen: Synthetic peptid from the coding sequence of murine 25(OH)-Vitamin-D3-1-alpha-Hydroxylase (aa 266-289)

Format: Liquid

Isotype: IgG  (Matching secondary antibodies)

Description: Sheep IgG fraction in glycine buffered NaCl solution pH 7.4, contains 0.1% sodium azide, 0.1% Epsilon-amino-n-caproic acid, 0.01% Benzamidine and 1 mM EDTA

Specificity: 25(OH)Vitamin D3-1-alpha-Hydroxylase, 56 kDa Protein in Western Blot

Application Details

Concentration: app. 7 mg/ml

Storage: 2-8°C

Restrictions: For Research Use only

Publications

Publications: Takeyama, Kitanaka, Sato et al.: "25-Hydroxyvitamin D3 1alpha-hydroxylase and vitamin D synthesis." in: Science (New York, N.Y.), Vol. 277, Issue 5333, pp. 1827-30, 1997 (PubMed).

Bland, Walker, Hughes et al.: "Constitutive expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in a transformed human proximal tubule cell line: evidence for direct regulation of vitamin D metabolism by calcium." in: Endocrinology, Vol. 140, Issue 5, pp. 2027-34, 1999 (PubMed).

Zehnder, Bland, Walker et al.: "Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in the human kidney." in: Journal of the American Society of Nephrology : JASN, Vol. 10, Issue 12, pp. 2465-73, 2000 (PubMed).

Bland, Markovic, Hills et al.: "Expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in pancreatic islets." in: The Journal of steroid biochemistry and molecular biology, Vol. 89-90, Issue 1-5, pp. 121-5, 2004 (PubMed).

Agic, Xu, Altgassen et al.: "Relative expression of 1,25-dihydroxyvitamin D3 receptor, vitamin D 1 alpha-hydroxylase, vitamin D 24-hydroxylase, and vitamin D 25-hydroxylase in endometriosis and gynecologic cancers." in: Reproductive sciences (Thousand Oaks, Calif.), Vol. 14, Issue 5, pp. 486-97, 2007 (PubMed).