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Antibodies
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anti-Coagulation Factor VIII (F8) antibody
Coagulation Factor VIII (F8) antibody
| Antigen |
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| Synonyms |
AHF, F8B, F8C, HEMA, FVIII, DXS1253E, F8, Cf8, Cf-8, fb61d02, wu:fb61d02 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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Western Blotting (WB) (42), Enzyme Immunoassay (EIA) (29), ELISA (21), To be determined by user (TBD) (7), ELISA (Detection) (6), Immunohistochemistry (Frozen Sections) (IHC (fro)) (4), Immunohistochemistry (IHC) (3), Functional Studies (Func) (1), Immunodiffusion (ID) (1), Immunoelectrophoresis (IEP) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1), Immunoprecipitation (IP) (1), Radioimmunoassay (RIA) (1)
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| Catalog no. |
ABIN249391 |
| Quantity |
200 ul (IgG concentration is 22.2 µg/µl) |
| Price |
473.20 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 3 to 5 Business Days |
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Immunogen
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purified full length native human Coagulation Factor VIII-VWF-F VIII:c complex
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Format
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Liquid
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Description
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The factor VIII complex, with a molecular weight in excess of 1 million, has 2components: (1) factor VIII P00451 (molecular weight of 267 kDa) called factorVIII C, when measured by procoagulant activity or factor VIII Ag, when measuredimmunologically, (2) factor VIII R P04275 (the von Willebrand factor or vWF) hasa molecular weight of 225 kDa. Factor VIII, along with calcium and phospholipids,acts as a cofactor for factor IXa when it converts factor X to the activated form,factor Xa. Domain F5/8 type C 2 Is responsible for phospholipid binding andessential for factor VIII activity. Defects in F8 are the cause of hemophilia A (HEMA). HEMA is a common recessive X-linked coagulation disorder.
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Specificity
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Predicted reactivity: human.
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Application Notes
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Recommended Dilution 1: 200 (IHC).
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Concentration
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IgG concentration is 22.2 µg/µl
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Buffer
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Total IgY fraction at 20 mg/ml in 0.9% NaCl, 0.1% sodiumazide
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Storage
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store at 4°C, make aliquots to avoid working with a stock. Please, remember tospin tubes briefly prior to opening them to avoid any losses that might occur fromliquid material adhering to the cap or sides of the tubes.
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Restrictions
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For Research Use only
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Alternatives for antigen "Coagulation Factor VIII (F8)", type "Antibodies"
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Hosts
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Mouse (45), Sheep (11), Rabbit (9), Rat (5)
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Reactivities
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Human (50), Mouse (Murine) (7), Dog (Canine) (2), Pig (Porcine) (1)
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Applications
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Western Blotting (WB) (42), Enzyme Immunoassay (EIA) (29), ELISA (21), To be determined by user (TBD) (7), ELISA (Detection) (6), Immunohistochemistry (Frozen Sections) (IHC (fro)) (4), Immunohistochemistry (IHC) (3), Functional Studies (Func) (1), Immunodiffusion (ID) (1), Immunoelectrophoresis (IEP) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1), Immunoprecipitation (IP) (1), Radioimmunoassay (RIA) (1)
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Conjugates
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HRP (2), Alkaline Phosphatase (AP) (1), Biotin (1), FITC (1)
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Epitopes
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Factor 8c (24), A2 domain (3), Factor 8 (2), Heavy chain (1)
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Alternatives 
